Prof. Nikolai Vassilev

Prof. Nikolai Vassilev

Prof. Nikolai Vassilev

(room 112)

Name: Nikolay Vassilev

Phone: +359 2 9606 172

E-mail: Nikolay.Vassilev@orgchm.bas.bg

ORCID: 0000-0002-8781-2866

Scopus ID: 7004497254

Research interests/Area of expertise:

– Structural analysis and stereochemistry of synthetic organic compounds, especially organophosphorus compounds and complexes;

– Molecular mobility – classical dynamic NMR for the investigation of tautomeric and conformational equilibria;

– NMR-Based Metabolomics of natural extracts and biofluids;

– NMR spectroscopy with in situ UV/Vis irradiation

– NMR methodology

– Application of computational methods for structural elucidation and for proving mechanisms of organic rearrangements.

 

Academic career:

2017 – present  Full Professor, Bulgarian NMR Centre, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

2010 – 2017      Associate Professor, Bulgarian NMR Centre, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

2006 – 2010      Research Associate I degree, NMR Laboratory, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

1997 – 2006      Research Associate II degree, NMR Laboratory, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

1994 – 1997      Research Associate III degree, NMR Laboratory, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

1988 – 1994      Researcher, NMR Laboratory, NMR Laboratory, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

 

Education:

2006     PhD in organic chemistry, NMR Laboratory, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences

Thesis: “Specific applications and development of NMR methods for the investigation of molecular mobility”, supervisor Prof. DSc. Valentin Dimitrov

1988     MSc in chemistry (specialization: Chemical Physics and Theoretical Chemistry) Sofia University “St. Kliment Ohridski”, Faculty of Chemistry and Pharmacy.

1982 – 1988      Student in Sofia University “St. Kliment Ohridski”, Faculty of Chemistry and Pharmacy. All general courses in chemistry, with specialization in organic and analytical chemistry.

Awards:

  • Best poster award at 18th Central and Eastern European NMR Symposium & Bruker User’s Meeting, 2016, Sofia, Bulgaria
  • Best poster award at 11th European Workshop on Phosphorus Chemistry, 2014, Sofia, Bulgaria

Selected publications:

2023     Dobrikov, G.M., Nikolova, Y., Slavchev, I., Dangalov, M., Deneva, V., Antonov, L., Vassilev, N.G., “Structure and Conformational Mobility of OLED-Relevant 1,3,5-Triazine Derivatives”, Molecules, 28, 1248 (link)

2021     Dangalov, M., Petrov, P., Vassilev, N.G. “N-heterocyclic bis-carbene palladium complexes derived from functionalized naphthalimides–Synthesis, Structure elucidation and DFT study.”, Journal of Molecular Structure, 1230, 129944. (link)

2020     Toncheva-Moncheva, N., Dangalov, M., Vassilev, N.G., Novakov, C.P., Novakov, C.P. Thiol-ene coupling reaction achievement and monitoring by “: In situ ” UV irradiation NMR spectroscopy, RSC Advances, 10(42), 25214-25222. (link)

2020     Philipova, I., Stavrakov, G., Dimitrov, V., Vassilev, N., Galantamine derivatives: Synthesis, NMR study, DFT calculations and application in asymmetric catalysis, Journal of Molecular Structure, 1219, 128568. (link)

2019     Markova, N. V., Rogojerov, M. I., Angelova, V. T., Vassilev, N. G., “Experimental and theoretical conformational studies of hydrazine derivatives bearing a chromene scaffold”, Journal of Molecular Structure, 1198, 126880. (link)

2016     Dangalov, M., Stoyanova, M., Petrov, P., Putala, M., Vassilev, N. G., „Fluxional Pd (II) NHC complexes–Synthesis, structure elucidation and catalytic studies. Journal of Organometallic Chemistry, 817, 1-14. (link)

Active projects:

Participant in projects:

  • Creation and Development of Centre of Excellence “National center of mechatronics and clean technologies“ BG05M2OP001-1.001-0008-C01
  • Creation And Development Of Centres Of Competence „Sustainable utilization of bio-resources and waste of medicinal and aromatic plants for innovative bioactive products” BG05M2OP001-1.002-0012-C01
  • Creation And Development Of Centres Of Competence „Clean technologies for sustainable environment – waters, waste, energy for circular economy“ (Clean&Circle) BG05M2OP001-1.002-0019
  • National Research Programme “Innovative Low-Toxic Bioactive Systems for Precision Medicine (BioActiveMed)”
  • INFRAMAT: Distributed infrastructure of centers for synthesis and characterization of new materials and conservation of archeological and ethnographic artefacts’, part of the Bulgarian National Roadmap for Research Infrastructure Programme.

International collaborations and fellowships:

1995     Visiting researcher in University of Exeter, UK

2001-2002        Visiting researcher in University of York, UK

Selected publications