From basic experiments to advanced NMR techniques for characterization of liquid, semi-solid and solid materials


Liquid phase NMR spectroscopy

  • Structural analysis and stereochemistry of synthetic organic compounds
  • Molecular mobility – classical dynamic NMR for the investigation of tautomeric and conformational equilibria.
  • Diffusion NMR spectroscopy – investigation of supramolecular complexes, processes of self-aggregation, particle size determination in colloidal systems, analysis of complex mixtures.
  • Chemical profiling and metabolic analysis of extracts of plant origin
  • Analysis of food and natural products
  • NMR spectroscopy with in situ irradiation

Solid state NMR spectroscopy

  • Structure of mesoporous silicates and zeolites
  • Organic-inorganic hybrid materials

NMR spectroscopy of soft and semi-solid materials

  • Polymeric (hydro)gels
  • Extracts of medicinal and aromatic plants


The Bulgarian NMR Centre provides a broad range of routine as well as more advanced NMR service analyses.

Routine NMR analyses

First time customers need to contact the laboratory by e-mail for registration and for receiving a user name and password to access the NMR service platform

The routine analyses are performed on the Bruker AVNEO 400 spectrometer. You are kindly requested to complete a separate request form for each sample. More information about our requirements for sample preparation you can find here.

  • NMR spectra of liquid samples: 1Н, 13C{H}, DEPT135, DEPT90, 31P{H}, 31P, 19F{H}, 19F, NOE, COSY, NOESY, ROESY, HMQC, HSQC, HMBC, DOSY.
  • NMR spectra of solid samples: 13C, 31P, 15N, 7Li, 6Li, 11B, 29Si, 27Al, 23Na, 71Ga, 119Sn etc. with or without cross-polarization (CP-MAS) and/or high-power decoupling (HPDEC).

Advanced NMR analyses

For advanced NMR analyses, please, contact the head of the Bulgarian NMR Centre, Prof. Pavletta Shestakova to discuss your needs and to receive more information.